Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PARL | Q9H300 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29868031 | 0.77 | CRBN (0.47) | CRBNDDB1KMT2A | |
| SCHEMBL1028530 | 0.72 | MAP3K14 (0.39) | CRBNDDB1GAAMAPTPKM | |
| SCHEMBL193688 | 0.72 | MAP3K14 (0.39) | CRBNDDB1MAPTKMT2AMEN1 | |
| SCHEMBL3631245 | 0.71 | MAPT (0.47) | CRBNDDB1GAAALDH1A1MAPT | |
| SCHEMBL5855515 | 0.71 | MAP3K14 (0.39) | CRBNDDB1 | |
| SCHEMBL28825205 | 0.71 | PSEN1 (0.42) | MAPK1PARLALDH1A1MAPTKMT2A | |
| SCHEMBL10710886 | 0.70 | ACHE (0.45) | MAPK1PARLALDH1A1MAPTKMT2A | |
| SCHEMBL114367 | 0.69 | NPC1 (0.36) | CRBNDDB1GAAMAPTPKM | |
| SCHEMBL1929688 | 0.69 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL3381432 | 0.68 | MAP3K14 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300421-A | Synthetic substrate containing enzyme binding site linked to photographically active label and adsorbing structure | FUJI PHOTO FILM CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| EP-0048834-B1 | METHOD FOR MEASUREMENT OF TRACE ENZYMES | FUJI PHOTO FILM CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| US-4414325-A | PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| US-4414323-A | Method for measuring trace enzyme | FUJI PHOTO FILM CO., LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| EP-0048834-A1 | Method for measurement of trace enzymes | FUJI PHOTO FILM CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |