Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28227519 | 0.86 | SSTR4 (0.46) | SSTR4SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL28048694 | 0.77 | NCF1 (0.41) | SSTR4SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL28048808 | 0.76 | TLR8 (0.39) | SSTR4SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7408917 | 0.73 | SLC6A2 (0.43) | SSTR4SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL28227466 | 0.72 | SSTR4 (0.47) | SSTR4SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL4631199 | 0.72 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL1961849 | 0.72 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL28228207 | 0.72 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL28236498 | 0.70 | SLC6A2 (0.41) | SSTR4SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL6978722 | 0.70 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377851-A | BET bromodomain inhibitors and therapeutic methods using these inhibitors | UNIV MICHIGAN REGENTS | 2016-03-02 | — | — | CN | disclosed |