Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28051877 | 0.86 | CYP2C19 (0.39) | NPC1RAB9AALDH1A1CASP3SENP8 | |
| Hydrochloric Acid SCHEMBL30925343 | 0.77 | NPC1 (0.37) | PNMTNPC1RAB9AALDH1A1CASP3 | |
| SCHEMBL30606684 | 0.75 | PNMT (0.68) | PNMTNPC1RAB9AALDH1A1GABRA1 | |
| SCHEMBL633763 | 0.75 | PNMT (0.68) | PNMTNPC1RAB9AALDH1A1GABRA1 | |
| SCHEMBL27466300 | 0.75 | CYP2C19 (0.37) | NPC1RAB9AALDH1A1CASP3SENP8 | |
| SCHEMBL30122647 | 0.73 | PNMT (0.51) | PNMTNPC1RAB9AALDH1A1GABRA1 | |
| SCHEMBL27705952 | 0.72 | HSP90AA1 (0.43) | PNMTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14781410 | 0.72 | PTPN5 (0.48) | NPC1RAB9AALDH1A1CASP3SENP8 | |
| SCHEMBL3171441 | 0.72 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1CASP3SENP8 | |
| SCHEMBL7940042 | 0.72 | PNMT (0.38) | PNMTNPC1RAB9AALDH1A1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348330-A | 3 mono-substituted or 3,6 bis-substituted fluorenyl metalloscene and preparation method and application thereof | SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2016-02-24 | — | — | CN | disclosed |
| CN-105330508-A | 3-monosubstituted or 3,6-disubstituted fluorene derivative and preparing method and application thereof | SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2016-02-17 | — | — | CN | disclosed |