Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL28826007

C=CC(=O)OC.NC(=O)/C=C\C(=O)O

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.56
ALDH1A1 P00352 6/20 0.46
ALOX15 P16050 2/20 0.46
RECQL P46063 2/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPT P10636 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
KDM4E B2RXH2 1/20 0.44
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
TSHR P16473 5/20 0.39
FGFR4 P22455 1/20 0.39
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36
LMNA P02545 1/20 0.35
GAA P10253 2/20 0.33
HTT P42858 1/20 0.33
GFPT1 Q06210 1/20 0.32
CACNA1B Q00975 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL28826008 0.92 HCAR2 (0.48) HCAR2ALDH1A1ALOX15RECQLHSD17B10
Maleic Acid SCHEMBL11375082 0.89 HCAR2 (0.68) HCAR2ALDH1A1ALOX15RECQLHSD17B10
Maleic Acid SCHEMBL27466895 0.89 HCAR2 (0.68) HCAR2ALDH1A1ALOX15RECQLHSD17B10
Maleic Acid SCHEMBL27532368 0.87 HCAR2 (0.65) HCAR2ALDH1A1ALOX15RECQLHSD17B10
Maleic Acid SCHEMBL28245132 0.87 HCAR2 (0.65) HCAR2ALDH1A1ALOX15RECQLHSD17B10
Acrylic Acid Methyl Ester SCHEMBL9156494 0.85 ALDH1A1 (0.50) HCAR2ALDH1A1ALOX15RECQLHSD17B10
Acrylic Acid Methyl Ester SCHEMBL25290877 0.83 HCAR2 (0.46) HCAR2ALDH1A1ALOX15RECQLHSD17B10
Acrylic Acid Methyl Ester SCHEMBL11068393 0.83 ALDH1A1 (0.58) HCAR2ALDH1A1ALOX15RECQLHSD17B10
Acrylic Acid Methyl Ester SCHEMBL9648509 0.83 ALDH1A1 (0.58) HCAR2ALDH1A1ALOX15RECQLHSD17B10
Acrylic Acid Methyl Ester SCHEMBL27902028 0.81 HCAR2 (0.43) HCAR2ALDH1A1ALOX15RECQLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103586456-B A kind of High-dispersity silver powder and preparation method thereof and application GUANGZHOU CHEMISTRY CO., LTD. CHINESE ACADEMY OF SCIENCES (CN) 2016-01-20 CN claimed