Biphenyl

Biphenyl

SCHEMBL28826337

CN.Cc1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.69

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.69
LMNA P02545 1/20 0.69
TSHR P16473 1/20 0.69
ALOX12 P18054 1/20 0.69
ALDH1A1 P00352 3/20 0.56
TDP1 Q9NUW8 4/20 0.48
TAAR1 Q96RJ0 2/20 0.48
CYP3A4 P08684 1/20 0.48
HSD17B10 Q99714 1/20 0.48
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
HPGD P15428 3/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
NFKB1 P19838 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
SLC22A2 O15244 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7930008 0.94 ACHE (0.79) ACHELMNATSHRALOX12ALDH1A1
Biphenyl SCHEMBL28828599 0.94 ACHE (0.79) ACHELMNATSHRALOX12ALDH1A1
Biphenyl SCHEMBL27832408 0.90 ACHE (0.73) ACHELMNATSHRALOX12ALDH1A1
Biphenyl SCHEMBL27777225 0.90 ACHE (0.73) ACHELMNATSHRALOX12ALDH1A1
Tannin Pyrogallol SCHEMBL28563583 0.90 LMNA (0.73) ACHELMNATSHRALOX12ALDH1A1
Biphenyl SCHEMBL10908072 0.90 ACHE (0.73) ACHELMNATSHRALOX12ALDH1A1
Biphenyl SCHEMBL10906998 0.90 ACHE (0.73) ACHELMNATSHRALOX12ALDH1A1
Biphenyl SCHEMBL27663822 0.90 ACHE (0.73) ACHELMNATSHRALOX12ALDH1A1
Toluene SCHEMBL2508427 0.90
Toluene SCHEMBL27666116 0.90 ACHE (0.85) ACHELMNATSHRALOX12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103380137-B The nitrogen-containing heterocycle compound of a kind of N ortho position acyl substituted and contracting amine thereof close the preparation method of iron (II) title complex CHINA PETROLEUM & CHEMICAL CORP. (CN) 2016-02-10 CN disclosed