Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL964683 | 0.81 | RXRA (0.50) | RXRARXRBCASRPTPN5GABRA1 | |
| SCHEMBL28036144 | 0.81 | CASR (0.58) | CASRAKR1C3AKR1C2CYP1A2CYP2C19 | |
| SCHEMBL30516664 | 0.81 | CASR (0.58) | CASRAKR1C3AKR1C2CYP1A2CYP2C19 | |
| SCHEMBL4053854 | 0.81 | VSIR (0.55) | L3MBTL1MAPT | |
| SCHEMBL964681 | 0.80 | RXRA (0.49) | RXRARXRBPTPN5GABRA1GABRG2 | |
| SCHEMBL8469211 | 0.78 | RXRA (0.72) | RXRARXRBPTPN5GABRA1GABRG2 | |
| SCHEMBL16334238 | 0.78 | RXRA (0.54) | RXRARXRBPTPN5GABRA1GABRG2 | |
| SCHEMBL13608268 | 0.76 | MEN1 (0.39) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1336946 | 0.75 | RXRA (0.51) | RXRARXRBPTPN5GABRA1GABRG2 | |
| SCHEMBL12856837 | 0.75 | PTPRC (0.55) | PTPRCPTPN1KAT6AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105392777-A | Biaryl derivatives as GRP120 agonists | LG LIFE SCIENCES LTD | 2016-03-09 | — | — | CN | disclosed |