Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2762000 | 0.99 | EPHX1 (0.54) | EPHX1P4HTMMEN1KMT2ACYP1A2 | |
| SCHEMBL17479494 | 0.87 | P4HTM (0.50) | EPHX1P4HTMCYP1A2MMECPA1 | |
| Ammonia Solution, Strong SCHEMBL27723189 | 0.86 | KMT2A (0.40) | EPHX1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17479462 | 0.86 | P4HTM (0.49) | EPHX1P4HTMMEN1KMT2ACYP1A2 | |
| Lithium SCHEMBL17479466 | 0.86 | P4HTM (0.49) | EPHX1P4HTMMEN1KMT2ACYP1A2 | |
| Lithium Ion SCHEMBL17479463 | 0.83 | ALPL (0.41) | EPHX1P4HTMMEN1KMT2ACYP1A2 | |
| SCHEMBL17477792 | 0.81 | MEN1 (0.45) | MEN1KMT2AHDAC8ALDH1A1NPC1 | |
| SCHEMBL17477824 | 0.80 | GPR119 (0.48) | P4HTMMEN1KMT2ACYP1A2HDAC8 | |
| SCHEMBL30637642 | 0.78 | EPHX1 (0.53) | EPHX1P4HTMMEN1KMT2ACYP1A2 | |
| SCHEMBL18945036 | 0.76 | EPHX1 (0.42) | EPHX1CYP1A2ALDH1A1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103274961-B | The Compounds and methods for for the treatment of cell generation disorders | KINEX PHARMACEUTICALS LLC (US) | 2016-05-18 | — | — | CN | disclosed |