SCHEMBL28827007

SCHEMBL28827007

C=CCc1cccc(C(O)(O)c2ccccc2)c1CC=C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.41
GABRB2 P47870 2/20 0.41
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 2/20 0.34
AURKA O14965 1/20 0.33
DAPK3 O43293 1/20 0.33
MAP4K4 O95819 1/20 0.33
RET P07949 1/20 0.33
IGF1R P08069 1/20 0.33
MET P08581 1/20 0.33
PIM1 P11309 1/20 0.33
LTK P29376 1/20 0.33
KDR P35968 1/20 0.33
MAPK8 P45983 1/20 0.33
MAPK9 P45984 1/20 0.33
CDK8 P49336 1/20 0.33
CLK2 P49760 1/20 0.33
CDK9 P50750 1/20 0.33
CDK5 Q00535 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28233471 0.84 GABRA1 (0.40) GABRA1GABRB2ALDH1A1TSHRHTT
SCHEMBL4170464 0.80 ALDH1A1 (0.38) GABRA1GABRB2ALDH1A1TSHRHTT
SCHEMBL9471419 0.76 GABRA1 (0.41) GABRA1GABRB2ALDH1A1TSHRHTT
SCHEMBL8979346 0.76 GABRA1 (0.34) GABRA1GABRB2ALDH1A1TSHRLMNA
SCHEMBL11054212 0.75 GABRA1 (0.43) GABRA1GABRB2ALDH1A1AKR1B1KMT2A
SCHEMBL170076 0.75 ALDH1A1 (0.37) GABRA1GABRB2ALDH1A1TSHRHTT
SCHEMBL18694874 0.74 GABRA1 (0.41) GABRA1GABRB2ALDH1A1TSHRHTT
SCHEMBL18136 0.73 GABRA1 (0.56) GABRA1GABRB2ALDH1A1AURKADAPK3
Hydrochloric Acid SCHEMBL859874 0.71 GABRA1 (0.40) GABRA1GABRB2ALDH1A1AKR1B1KMT2A
SCHEMBL10614506 0.71 GABRA1 (0.40) GABRA1GABRB2AKR1B1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114671741-A Resorcinol oligomeric derivative for rubber tire and preparation and application of masterbatch particle of resorcinol oligomeric derivative 彤程新材料集团股份有限公司 2022-06-28 CN disclosed