Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422360 | 0.82 | TSHR (0.41) | ALDH1A1CYP3A4LMNAIDO1AOC3 | |
| SCHEMBL17705682 | 0.80 | CARM1 (0.63) | ALDH1A1CYP3A4LMNAIDO1AOC3 | |
| SCHEMBL4081568 | 0.79 | HTT (0.55) | ALDH1A1AOC3TSHRHDAC3HDAC1 | |
| SCHEMBL16081620 | 0.79 | ATM (0.54) | ALDH1A1CYP3A4AOC3TSHRNPC1 | |
| SCHEMBL11293490 | 0.79 | CARM1 (0.47) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL28241166 | 0.78 | MEN1 (0.61) | MAOAMAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL6165777 | 0.78 | L3MBTL1 (0.53) | ALDH1A1LMNATSHRMAPTHDAC3 | |
| SCHEMBL21121016 | 0.77 | CARM1 (0.46) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL19326604 | 0.77 | HTT (0.53) | ALDH1A1AOC3TSHRHDAC3HDAC1 | |
| SCHEMBL9329761 | 0.77 | HTT (0.53) | ALDH1A1AOC3TSHRHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105601741-A | Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer | COMPUGEN LTD | 2016-05-25 | — | — | CN | disclosed |