Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.63 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.63 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18065732 | 0.87 | SIGMAR1 (0.62) | CARM1PRMT6PRMT8SIGMAR1TMEM97 | |
| SCHEMBL1268109 | 0.82 | CARM1 (0.60) | CARM1PRMT6PRMT8SIGMAR1TMEM97 | |
| SCHEMBL7055109 | 0.81 | CARM1 (0.75) | CARM1PRMT6PRMT8SIGMAR1TSHR | |
| Hydrochloric Acid SCHEMBL5463194 | 0.81 | CARM1 (0.58) | CARM1PRMT6PRMT8SIGMAR1TMEM97 | |
| SCHEMBL28827019 | 0.80 | ALDH1A1 (0.54) | CARM1PRMT6PRMT8TSHRALDH1A1 | |
| SCHEMBL8944637 | 0.79 | SIGMAR1 (0.68) | CARM1PRMT6PRMT8SIGMAR1TMEM97 | |
| SCHEMBL13991801 | 0.79 | CARM1 (0.56) | CARM1PRMT6PRMT8SIGMAR1TMEM97 | |
| SCHEMBL11117998 | 0.79 | CARM1 (0.56) | CARM1PRMT6PRMT8SIGMAR1TMEM97 | |
| SCHEMBL11322171 | 0.79 | ROCK2 (0.57) | CARM1PRMT6PRMT8SIGMAR1TMEM97 | |
| SCHEMBL11117996 | 0.78 | CARM1 (0.55) | CARM1PRMT6PRMT8SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160114042-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114042-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | ABCB4, PHOSPHO1, SGMS2 | CARM1 699/4885PRMT6 665/4885PRMT8 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.