SCHEMBL28827150

SCHEMBL28827150

CCCCCC1(OC(C)=O)CCCC1=O

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.40
CYP19A1 P11511 1/20 0.32
ALDH1A1 P00352 2/20 0.32
PRKCA P17252 5/20 0.32
CCR2 P41597 1/20 0.30
CETP P11597 1/20 0.30
DNTT P04053 1/20 0.30
POLB P06746 1/20 0.30
POLA1 P09884 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8315536 0.84 CYP19A1 (0.33) CYP19A1CETP
SCHEMBL1254598 0.82 MAPT (0.31) CYP19A1
SCHEMBL28923814 0.81 SIRT2 (0.41) SIRT2CYP19A1PRKCA
SCHEMBL8654847 0.78 GRIN2D (0.35) CYP19A1
SCHEMBL21121157 0.75
Acetic Acid SCHEMBL30206922 0.72 SIRT2 (0.42) SIRT2CYP19A1PRKCACCR2CETP
SCHEMBL10704801 0.72 SIRT2 (0.33) SIRT2
SCHEMBL15295443 0.71 SIRT2 (0.41) SIRT2CYP19A1PRKCACCR2CETP
SCHEMBL29290134 0.70 ALDH1A1 (0.36) SIRT2ALDH1A1CETP
SCHEMBL4810386 0.70 SIRT2 (0.40) SIRT2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415293-B Dehydrogenation reaction 弗门尼舍有限公司 2022-08-02 CN disclosed