Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296760 | 0.83 | ATM (0.43) | CYP2D6DRD2DRD4OPRM1DRD3 | |
| SCHEMBL7030622 | 0.75 | MAPK1 (0.46) | CYP2D6DRD2DRD4OPRM1DRD3 | |
| SCHEMBL1058732 | 0.74 | MAPK1 (0.55) | MAPK1CYP3A4ALDH1A1TAAR1ALOX15 | |
| SCHEMBL8655165 | 0.74 | CYP2D6 (0.42) | CYP2D6DRD2DRD4OPRM1DRD3 | |
| SCHEMBL11761265 | 0.74 | CYP2D6 (0.40) | CYP2D6DRD2DRD4OPRM1DRD3 | |
| SCHEMBL5875525 | 0.73 | MAPK1 (0.44) | CYP2D6DRD2DRD4OPRM1DRD3 | |
| SCHEMBL230672 | 0.73 | MAPK1 (0.44) | CYP2D6DRD2DRD4OPRM1DRD3 | |
| SCHEMBL1021158 | 0.73 | GRM1 (0.49) | CYP2D6DRD2DRD4OPRM1DRD3 | |
| SCHEMBL6735941 | 0.72 | MAPK1 (0.48) | MAPK1CYP3A4ALDH1A1TAAR1ALOX15 | |
| SCHEMBL20629458 | 0.71 | CYP2D6 (0.42) | CYP2D6DRD2DRD4OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114952608-A | Fixed abrasive grinding pad based on photo-initiated front-end polymerization reaction and preparation method thereof | 郑州磨料磨具磨削研究所有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-115677890-A | Dendritic fluorescent liquid crystal polymer with aggregation-induced emission characteristic and preparation method thereof | 湖南理工学院 | 2023-02-03 | — | — | CN | disclosed |
| CN-114952608-A | Fixed abrasive grinding pad based on photo-initiated front-end polymerization reaction and preparation method thereof | 郑州磨料磨具磨削研究所有限公司 | 2022-08-30 | — | — | CN | disclosed |