SCHEMBL1058732

SCHEMBL1058732

CC(c1ccccc1)(c1ccccc1)C(C)(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.55
ALDH1A1 P00352 3/20 0.50
TAAR1 Q96RJ0 1/20 0.50
ALOX15 P16050 1/20 0.50
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
CYP3A4 P08684 1/20 0.48
KCNN4 O15554 4/20 0.48
TSHR P16473 2/20 0.47
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
CYP2B6 P20813 1/20 0.42
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8571104 0.87 MAPK1 (0.50) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL10865633 0.84 MAPK1 (0.48) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL6735941 0.84 MAPK1 (0.48) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL26253711 0.82 MAPK1 (0.46) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL27652170 0.82 ALDH1A1 (0.48) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL416115 0.82 ALDH1A1 (0.48) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL730686 0.82 ALDH1A1 (0.48) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL5079313 0.82 ALDH1A1 (0.52) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL28946944 0.80 MAPK1 (0.50) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL25260949 0.80 ALDH1A1 (0.46) MAPK1ALDH1A1TAAR1ALOX15ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3126419-B1 FREE RADICAL GRAFTING OF FUNCTIONALIZED RESINS FOR TIRES EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-01-22 EP claimed
US-10059782-B2 Free radical grafting of functionalized resins for tires EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-08-28 US claimed
US-20170058058-A1 Free Radical Grafting of Functionalized Resins for Tires EXXONMOBIL CHEMICAL PATENTS INC. 2017-03-02 US claimed
EP-3126419-A1 FREE RADICAL GRAFTING OF FUNCTIONALIZED RESINS FOR TIRES ExxonMobil Chemical Patents Inc. (US) 2017-02-08 EP claimed
CN-106133014-A Free radical grafting of functionalized resins for tires 埃克森美孚化学专利公司 2016-11-16 CN claimed
WO-2015153058-A1 FREE RADICAL GRAFTING OF FUNCTIONALIZED RESINS FOR TIRES EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-10-08 WO claimed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-12570774-B2 Cycloolefin resin cured product having oxygen barrier properties RIMTEC CORPORATION (JP) 2026-03-10 US disclosed
EP-4703402-A1 POLYMERIZABLE COMPOSITION AND MOLDED ARTICLE RIMTEC Corporation (JP) 2026-03-04 EP disclosed
EP-3960414-B1 METHOD FOR PRODUCING CYCLOOLEFIN RESIN-DECORATIVE MOLDED ARTICLE RIMTEC CORP (JP) 2025-08-06 EP disclosed
US-12343905-B2 Method for producing cycloolefin resin-decorative molded article RIMTEC CORPORATION (JP) 2025-07-01 US disclosed
WO-2024224997-A1 POLYMERIZABLE COMPOSITION AND MOLDED ARTICLE RIMTEC株式会社 2024-10-31 WO disclosed
US-20240287234-A1 COMPOSITE MATERIAL AND MOLDED COMPOSITE MATERIAL RIMTEC CORPORATION (JP) 2024-08-29 US disclosed
EP-0416430-A1 Thermoplastic moulding composition with increased heat deformation resistance BASF Aktiengesellschaft (DE) 1991-03-13 EP disclosed
EP-0407832-A2 Reinforced coloured thermoplastic mouldings based on polyamides and polyphenyleneethers BASF Aktiengesellschaft (DE) 1991-01-16 EP disclosed
EP-0400418-A1 Thermoplastic mouldings based on polyamide and polyphenylenether BASF Aktiengesellschaft (DE) 1990-12-05 EP disclosed
EP-0387824-A2 Thermoplastic molding masses on the basis of impact modified polyamide and functionalised polyphenylenether BASF Aktiengesellschaft (DE) 1990-09-19 EP disclosed
EP-0144015-B1 SELF-EXTINGUISHING COMPOSITIONS BASED ON ETHYLENE VINYLACETATE COPOLYMERS SUITABLE FOR THE PREPARATION OF FOAMED MATERIALS MONTEDIPE S.p.A. (IT) 1988-09-14 EP disclosed
EP-0020922-A1 Process for increasing the stability of oxidation-sensitive organic additives, especially of fluorescence dyestuffs, in radically polymerizable systems, such as casting masses or casting resins SIEMENS AKTIENGESELLSCHAFT (DE) 1981-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570774-B2 Cycloolefin resin cured product having oxygen barrier properties HMOX1, GPX1, ALOX12 MAPK1 2323/4885ALDH1A1 467/4885TAAR1 2331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.