SCHEMBL8655165

SCHEMBL8655165

CCC(c1ccccc1)(c1ccccc1)C(C#N)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.42
DRD2 P14416 2/20 0.42
DRD4 P21917 2/20 0.42
OPRM1 P35372 2/20 0.42
DRD3 P35462 2/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 2/20 0.40
ATM Q13315 1/20 0.39
KCNN4 O15554 2/20 0.38
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CHRM3 P20309 4/20 0.35
CHRM2 P08172 2/20 0.35
CHRM1 P11229 2/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
KCNA3 P22001 2/20 0.34
EBP Q15125 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296760 0.79 ATM (0.43) CYP2D6DRD2DRD4OPRM1DRD3
SCHEMBL1059140 0.79 KCNN4 (0.48) LMNACYP3A4KCNN4CYP2C19ALDH1A1
SCHEMBL6740246 0.78 KCNN4 (0.43) LMNAKCNN4CYP2C19ALDH1A1TAAR1
SCHEMBL18940705 0.74 DRD2 (0.42) CYP2D6DRD2DRD4OPRM1DRD3
SCHEMBL13271382 0.74 CYP2D6 (0.44) CYP2D6DRD2DRD4OPRM1DRD3
SCHEMBL28827192 0.74 CYP2D6 (0.40) CYP2D6DRD2DRD4OPRM1DRD3
SCHEMBL3979738 0.74 CYP2D6 (0.58) CYP2D6DRD2DRD4OPRM1DRD3
SCHEMBL6284814 0.74 ATM (0.46) CYP2D6DRD2DRD4OPRM1DRD3
SCHEMBL10871195 0.73 CYP2D6 (0.40) CYP2D6DRD2DRD4OPRM1DRD3
SCHEMBL7932124 0.73 TAAR1 (0.44) CYP3A4KCNN4CYP2C19ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723250-A Process for image formation using liquid developer FUJI XEROX CO., LTD. (JP) 1998-03-03 US disclosed