SCHEMBL28827345

SCHEMBL28827345

CCCCCCC1(CCOCc2ccccc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
CETP P11597 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
MMP2 P08253 2/20 0.40
MMP9 P14780 2/20 0.40
MMP8 P22894 2/20 0.40
MMP13 P45452 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
TSHR P16473 2/20 0.40
EPHX2 P34913 1/20 0.39
LTA4H P09960 1/20 0.38
PTPN1 P18031 1/20 0.38
CDC25B P30305 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
NR5A2 O00482 1/20 0.37
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
OPRK1 P41145 1/20 0.37
OPRL1 P41146 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23533368 1.00 ALDH1A1 (0.42) ALDH1A1CETPL3MBTL1MMP2MMP9
SCHEMBL16057438 0.79 L3MBTL1 (0.58) ALDH1A1CETPL3MBTL1TDP1TSHR
SCHEMBL11995970 0.79 L3MBTL1 (0.58) ALDH1A1CETPL3MBTL1TDP1TSHR
SCHEMBL7517468 0.79 L3MBTL1 (0.58) ALDH1A1CETPL3MBTL1TDP1TSHR
SCHEMBL14526009 0.79 L3MBTL1 (0.58) ALDH1A1CETPL3MBTL1TDP1TSHR
SCHEMBL6685708 0.79 L3MBTL1 (0.58) ALDH1A1CETPL3MBTL1TDP1TSHR
SCHEMBL7120703 0.79 L3MBTL1 (0.58) ALDH1A1CETPL3MBTL1TDP1TSHR
SCHEMBL2886385 0.79 L3MBTL1 (0.58) ALDH1A1CETPL3MBTL1TDP1TSHR
SCHEMBL21081916 0.79 L3MBTL1 (0.58) ALDH1A1CETPL3MBTL1TDP1TSHR
SCHEMBL2231686 0.79 L3MBTL1 (0.58) ALDH1A1CETPL3MBTL1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114828958-A Cycloalkyl-containing carboxylic acids and use thereof 里米诺生物科学有限公司 2022-07-29 CN disclosed