Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3433075 | 0.89 | CA2 (0.67) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL1535886 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTRAB9A | |
| SCHEMBL5962921 | 0.81 | CA2 (0.70) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL3215328 | 0.81 | ALDH1A1 (0.61) | CA2CA1GSK3BALDH1A1MAPT | |
| SCHEMBL9856491 | 0.80 | GSK3B (0.54) | GSK3BVNN1 | |
| SCHEMBL9694596 | 0.79 | TSHR (0.59) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL13403832 | 0.79 | CA2 (0.55) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL4811505 | 0.79 | CA1 (0.55) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL9183599 | 0.79 | CA2 (0.55) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL507820 | 0.79 | ALDH1A1 (0.67) | CA2CA1GSK3BPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776893-B2 | Use of PDE4 inhibitors for the treatment of diabetes mellitus | NYCOMED GMBH (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20060281745-A1 | Use of pde4 inhibitors for the treatment of diabetes mellitus | ALTANA PHARMA AG (DE) | 2006-12-14 | — | — | US | disclosed |
| EP-1650193-A2 | 6-Phenylphenanthridines with PDE-IV inhibiting activity | ALTANA Pharma AG (DE) | 2006-04-26 | — | — | EP | disclosed |
| EP-1147089-B1 | PHENYLPHENANTHRIDINES WITH PDE-IV INHIBITING ACTIVITY | ALTANA PHARMA AG (DE) | 2005-12-07 | — | — | EP | disclosed |
| WO-2005023253-A1 | USE OF PDE4 INHIBITORS FOR THE TREATMENT OF DIABETES MELLITUS | ALTANA PHARMA AG (DE) | 2005-03-17 | — | — | WO | disclosed |
| EP-1240177-B1 | BENZOPHENONE ALPHA-D-GLYCOPYRANOSIDES, PREPARATION AND THERAPEUTIC USE | FOURNIER LAB SA (FR) | 2003-07-02 | — | — | EP | disclosed |
| WO-2003002586-A1 | [4-(4-CYANOBENZOYL)PHENYL]GLYCOFURANOSIDE DERIVATIVES, USE OF SAID DERIVATIVES AS A MEDICAMENT, PRODUCTION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRES FOURNIER SA (FR) | 2003-01-09 | — | — | WO | disclosed |
| WO-2003002585-A1 | [4-(4-CYANOBENZOYL)PHENYL]GLYCOPYRANOSIDE DERIVATIVES, USE OF SAME AS A MEDICAMENT, PRODUCTION METHOD THEREOF AND COMPOSITIONS | LABORATOIRES FOURNIER SA (FR) | 2003-01-09 | — | — | WO | disclosed |
| US-6476025-B1 | Phenylphennanthridines with PDE-IV inhibiting activity | ALTANA PHARMA AG (DE) | 2002-11-05 | — | — | US | disclosed |
| EP-1240177-A2 | BENZOPHENONE ALPHA-D-GLYCOPYRANOSIDES, PREPARATION AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 2002-09-18 | — | — | EP | disclosed |
| EP-1240176-A1 | BENZOPHENONE GLYCOPYRANOSIDES, PREPARATION AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 2002-09-18 | — | — | EP | disclosed |
| EP-1147089-A1 | PHENYLPHENANTHRIDINES WITH PDE-IV INHIBITING ACTIVITY | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2001047940-A1 | BENZOPHENONE GLYCOPYRANOSIDES, PREPARATION AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 2001-07-05 | — | — | WO | disclosed |
| EP-1090017-A1 | NOVEL COMPOUNDS DERIVED FROM $g(a)-D-XYLOSE, PREPARATION METHOD AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000042020-A1 | PHENYLPHENANTHRIDINES WITH PDE-IV INHIBITING ACTIVITY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-07-20 | — | — | WO | disclosed |
| WO-1999067261-A1 | NOVEL COMPOUNDS DERIVED FROM α-D-XYLOSE, PREPARATION METHOD AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-12-29 | — | — | WO | disclosed |
| EP-0290321-B1 | BETA-D-PHENYL-THIOXYLOSIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | FOURNIER INDUSTRIE ET SANTE (FR) | 1991-10-02 | — | — | EP | disclosed |
| EP-0290321-A1 | Beta-D-phenyl-thioxylosides, process for their preparation and their use in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1988-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281745-A1 | Use of pde4 inhibitors for the treatment of diabetes mellitus | PDE4A, PDE4B, PDE12 | CA2 2608/4885CA1 4392/4885GSK3B 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.