Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | QDPR | P09417 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 4/20 | 0.38 |
| ▸ | HTR1B | P28222 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23166169 | 0.86 | CNR1 (0.52) | CNR1HTR6 | |
| SCHEMBL29760278 | 0.86 | CNR1 (0.52) | CNR1HTR6 | |
| SCHEMBL29268640 | 0.81 | TLR8 (0.46) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL28435263 | 0.79 | MAPT (0.50) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL28827483 | 0.78 | SMN1; SMN2 (0.40) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL28950016 | 0.78 | FLT3 (0.42) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL28827492 | 0.77 | KDM4E (0.41) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL28827489 | 0.76 | HPGD (0.39) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL25252564 | 0.74 | KDM4E (0.52) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL4776359 | 0.74 | MAPT (0.50) | LMNAMEN1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829350-B | Substituted carbazole compounds | 百时美施贵宝公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-114829350-A | Substituted carbazole compounds | 百时美施贵宝公司 | 2022-07-29 | — | — | CN | disclosed |