Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | QDPR | P09417 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28827472 | 0.89 | HPGD (0.37) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29760353 | 0.88 | BRD4 (0.51) | BRD4 | |
| SCHEMBL23167074 | 0.88 | BRD4 (0.51) | BRD4 | |
| SCHEMBL28827492 | 0.81 | KDM4E (0.41) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28950016 | 0.81 | FLT3 (0.42) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29268640 | 0.79 | TLR8 (0.46) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29760317 | 0.78 | BRD4 (0.49) | BRD4 | |
| SCHEMBL23166171 | 0.78 | BRD4 (0.49) | BRD4 | |
| SCHEMBL28827483 | 0.77 | SMN1; SMN2 (0.40) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28827480 | 0.76 | LMNA (0.44) | HPGDLMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829350-A | Substituted carbazole compounds | 百时美施贵宝公司 | 2022-07-29 | — | — | CN | disclosed |