SCHEMBL28828155

SCHEMBL28828155

O=C(CO)Nc1ncnc2nc[nH]c12

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 6/20 0.59
CYP3A4 P08684 1/20 0.59
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
NT5C2 P49902 2/20 0.54
CYP1A2 P05177 1/20 0.54
HIF1A Q16665 1/20 0.54
TSHR P16473 2/20 0.53
BRAF P15056 2/20 0.53
RECQL P46063 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HDAC1 Q13547 1/20 0.53
HDAC2 Q92769 1/20 0.53
TP53 P04637 1/20 0.52
HSD17B10 Q99714 1/20 0.52
NT5E P21589 1/20 0.52
HTT P42858 1/20 0.51
TOP2A P11388 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38663949 0.86 BRD4 (0.58) BRD4CYP3A4NPC1RAB9ANT5C2
SCHEMBL22118772 0.82 BRD4 (0.68) BRD4CYP3A4NPC1RAB9ANT5C2
SCHEMBL29475418 0.81 BRAF (0.72) BRD4CYP3A4NPC1RAB9ANT5C2
SCHEMBL5437612 0.81 BRD4 (0.62) BRD4CYP3A4NPC1RAB9ANT5C2
SCHEMBL536913 0.81 BRAF (0.72) BRD4CYP3A4NPC1RAB9ANT5C2
SCHEMBL38666421 0.80 BRD4 (0.66) BRD4NPC1RAB9ANT5C2CYP1A2
SCHEMBL7052324 0.79 HDAC1 (0.61) BRD4NPC1RAB9ATSHRSMN1; SMN2
SCHEMBL5192969 0.79 HDAC1 (0.61) BRD4NPC1RAB9ATSHRSMN1; SMN2
SCHEMBL29638098 0.79 NPC1 (0.56) BRD4CYP3A4NPC1RAB9ANT5C2
SCHEMBL17372610 0.79 NPC1 (0.56) BRD4CYP3A4NPC1RAB9ANT5C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117898208-A Method for promoting tissue culture regeneration of poplar by using carbon nano tube 天津大学 2024-04-19 CN claimed
CN-113735190-A Small-particle ternary precursor and preparation method thereof 南通金通储能动力新材料有限公司 2021-12-03 CN claimed
CN-112790060-A Method for updating old Chinese wampee trees 广西南亚热带农业科学研究所 2021-05-14 CN claimed
CN-112314438-A Culture method for acer yankee callus induction 杭州云树园艺有限公司 2021-02-05 CN claimed
CN-108849500-B Culture medium and method for lotus embryo rescue and rapid growth and development of offspring 武汉大学 2020-04-24 CN claimed
CN-117898208-A Method for promoting tissue culture regeneration of poplar by using carbon nano tube 天津大学 2024-04-19 CN disclosed
CN-116555333-B Application of Chinese wild rice ZlMYB1 and ZlMYB2 genes in improving anthocyanin content of rice seeds 中国农业科学院烟草研究所 2023-11-24 CN disclosed
CN-116555333-A Application of Chinese wild rice ZlMYB1 and ZlMYB2 genes in improving anthocyanin content of rice seeds 中国农业科学院烟草研究所 2023-08-08 CN disclosed
CN-116114693-A Mud flat saline-alkali soil rice growth promoter and preparation method thereof 江苏沿海生态科技发展有限公司 2023-05-16 CN disclosed
CN-114642171-B Induction method of high-activity tripterygium wilfordii metabolic products and tripterygium wilfordii active metabolic composition 华侨大学 2023-04-25 CN disclosed
CN-114642171-A Induction method of high-activity tripterygium wilfordii metabolite and tripterygium wilfordii active metabolic composition 华侨大学 2022-06-21 CN disclosed
CN-113735190-A Small-particle ternary precursor and preparation method thereof 南通金通储能动力新材料有限公司 2021-12-03 CN disclosed
CN-112790060-A Method for updating old Chinese wampee trees 广西南亚热带农业科学研究所 2021-05-14 CN disclosed
CN-112314438-A Culture method for acer yankee callus induction 杭州云树园艺有限公司 2021-02-05 CN disclosed
CN-107125135-B Method for efficiently inducing garlic embryonic callus by using rachis 南京农业大学 2020-08-04 CN disclosed
CN-106912299-B Grafting method of woody plant 河南红枫种苗股份有限公司 2020-05-08 CN disclosed
CN-108064689-B Tissue culture method of begonia aquifolium 四川七彩林科股份有限公司 2020-02-07 CN disclosed
CN-108450333-B Induction method of lilium tigrinum callus 长江师范学院 2020-02-07 CN disclosed
CN-108770688-B Rapid propagation method of murraya paniculata 华润三九医药股份有限公司 2020-02-07 CN disclosed
CN-105580735-A Culture solution capable of improving content of resveratrol in polygonum cuspidatum callus and culture method PROYA COSMETICS CO LTD 2016-05-18 CN disclosed