SCHEMBL38666421

SCHEMBL38666421

O=C(Cc1ccccc1)Nc1ncnc2nc[nH]c12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 9/20 0.66
MAPK1 P28482 2/20 0.61
LMNA P02545 2/20 0.61
TSHR P16473 2/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2D6 P10635 1/20 0.61
CDK2 P24941 1/20 0.61
NT5C2 P49902 2/20 0.60
HTT P42858 2/20 0.59
TAAR1 Q96RJ0 1/20 0.59
NT5E P21589 1/20 0.58
HSD17B10 Q99714 1/20 0.56
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
MEN1 O00255 1/20 0.52
TP53 P04637 1/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
KMT2A Q03164 1/20 0.52
TOP2A P11388 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6933558 0.82 BRD4 (0.63) BRD4MAPK1LMNATSHRCYP1A2
SCHEMBL30536136 0.82 BRD4 (0.63) BRD4MAPK1LMNATSHRCYP1A2
SCHEMBL6753015 0.81 BRD4 (0.62) BRD4MAPK1LMNATSHRCYP1A2
SCHEMBL28828155 0.80 BRD4 (0.59) BRD4TSHRCYP1A2NT5C2HTT
SCHEMBL2623137 0.80 NAMPT (0.50) BRD4MAPK1TSHRCDK2HSD17B10
SCHEMBL29514799 0.80 BRD4 (1.00) BRD4NT5C2NT5ENPC1RAB9A
SCHEMBL23124 0.80 BRD4 (1.00) BRD4NT5C2NT5ENPC1RAB9A
SCHEMBL38663949 0.79 BRD4 (0.58) BRD4TSHRCYP1A2NT5C2HTT
SCHEMBL3038563 0.78 NPC1 (0.76) BRD4MAPK1LMNATSHRCYP1A2
SCHEMBL8381776 0.78 BRD4 (0.97) BRD4NT5C2NT5ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO disclosed