SCHEMBL29475418

SCHEMBL29475418

CC(=O)Nc1ncnc2nc[nH]c12

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BRAF P15056 1/20 0.72
BRD4 O60885 9/20 0.62
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
CYP1A2 P05177 2/20 0.60
HIF1A Q16665 1/20 0.60
NT5C2 P49902 2/20 0.57
CDK2 P24941 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CREBBP Q92793 1/20 0.55
TP53 P04637 1/20 0.55
TSHR P16473 1/20 0.55
HSD17B10 Q99714 1/20 0.55
NT5E P21589 1/20 0.54
CYP3A4 P08684 1/20 0.54
HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536913 1.00 BRAF (0.72) BRAFBRD4NPC1RAB9ACYP1A2
SCHEMBL22118772 0.85 BRD4 (0.68) BRAFBRD4NPC1RAB9ACYP1A2
SCHEMBL5437612 0.83 BRD4 (0.62) BRAFBRD4NPC1RAB9ACYP1A2
SCHEMBL17362837 0.83 BRD4 (0.58) BRAFBRD4NPC1RAB9ACYP1A2
SCHEMBL29799431 0.83 BRD4 (0.58) BRAFBRD4NPC1RAB9ACYP1A2
SCHEMBL8720615 0.83 BRD4 (0.58) BRAFBRD4NPC1RAB9ACYP1A2
SCHEMBL8718918 0.81 BRD4 (0.57) BRAFBRD4NPC1RAB9ACYP1A2
SCHEMBL28828155 0.81 BRD4 (0.59) BRAFBRD4NPC1RAB9ACYP1A2
SCHEMBL28669706 0.81 NPC1 (0.63) BRAFBRD4NPC1RAB9ACYP1A2
SCHEMBL11481134 0.80 BRD4 (0.56) BRAFBRD4NPC1RAB9ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111430-A1 CHEMICAL MODIFICATIONS IN mRNA POLY(A) TAIL PRIME MEDICINE, INC. (US) 2025-05-30 WO claimed
EP-4687992-A1 LIPID-BASED NANOPARTICLE TARGETED AT ACTIVATED IMMUNE CELLS FOR THE EXPRESSION OF IMMUNE CELL INHIBITING MOLECULE AND USE THEREOF OSE IMMUNOTHERAPEUTICS (FR) 2026-02-11 EP disclosed
EP-4687991-A1 LIPID-BASED NANOPARTICLE TARGETED AT ACTIVATED IMMUNE CELLS FOR THE EXPRESSION OF IMMUNE CELL ENHANCING MOLECULE AND USE THEREOF OSE IMMUNOTHERAPEUTICS (FR) 2026-02-11 EP disclosed
WO-2025111452-A2 CHEMICAL MODIFICATIONS IN PEgRNA and ngRNAs PRIME MEDICINE, INC. (US) 2025-05-30 WO disclosed
WO-2025080995-A1 PHARMACEUTICAL AGENT-INTEGRIN LIGAND CONJUGATES FOR MUSCLE DELIVERY ADARX PHARMACEUTICALS, INC. (US) 2025-04-17 WO disclosed
US-20250108007-A1 LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION Suzhou Abogen Biosciences Co., Ltd. (CN) 2025-04-03 US disclosed
WO-2025052180-A2 LIPIDS AND LIPID NANOPARTICLES Axelyf ehf. (IS) 2025-03-13 WO disclosed
WO-2025036992-A1 RNA CONJUGATES CureVac SE (DE) 2025-02-20 WO disclosed
WO-2025038960-A1 OLIGONUCLEOTIDES CONTAINING A LIGAND AT AN INTERNAL POSITION ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 WO disclosed
WO-2024199282-A1 LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION 苏州艾博生物科技有限公司 2024-10-03 WO disclosed
WO-2024109798-A1 LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION 苏州艾博生物科技有限公司 2024-05-30 WO disclosed
WO-2024083171-A1 LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION 苏州艾博生物科技有限公司 2024-04-25 WO disclosed
WO-2024083172-A1 LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION 苏州艾博生物科技有限公司 2024-04-25 WO disclosed
CN-116064598-B Nucleic acid vaccine for coronavirus 苏州艾博生物科技有限公司 2024-03-12 CN disclosed
WO-2024022263-A1 LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION 苏州艾博生物科技有限公司 2024-02-01 WO disclosed
WO-2023116804-A1 LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION 苏州艾博生物科技有限公司 2023-06-29 WO disclosed
CN-116064598-A Nucleic acid vaccine for coronavirus 苏州艾博生物科技有限公司 2023-05-05 CN disclosed
WO-2023067560-A1 IONIZABLE CATIONIC COMPOUND Seqirus Inc. (US) 2023-04-27 WO disclosed
WO-2023067561-A1 IONIZABLE CATIONIC LIPID FOR MESSENGER RNA DELIVERY Seqirus Inc. (US) 2023-04-27 WO disclosed
WO-2022065413-A1 NOVEL ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF 株式会社理研ジェネシス 2022-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250108007-A1 LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION CETP, NPC1, LCAT BRAF 3131/4885BRD4 3013/4885NPC1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.