Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30064136 | 0.86 | SIRT3 (0.43) | SIRT3TDP1SMN1; SMN2POLBHPGD | |
| SCHEMBL1423953 | 0.86 | SIRT3 (0.43) | SIRT3TDP1SMN1; SMN2POLBHPGD | |
| SCHEMBL30171323 | 0.81 | HPGD (0.42) | SIRT3TDP1SMN1; SMN2POLBHPGD | |
| SCHEMBL28948291 | 0.81 | HPGD (0.42) | SIRT3TDP1SMN1; SMN2POLBHPGD | |
| SCHEMBL13162016 | 0.80 | SIRT3 (0.61) | SIRT3TDP1SMN1; SMN2SMYD3TYK2 | |
| SCHEMBL30107188 | 0.80 | SIRT3 (0.61) | SIRT3TDP1SMN1; SMN2SMYD3TYK2 | |
| SCHEMBL28064901 | 0.79 | POLB (0.57) | SMN1; SMN2POLBHPGDSYKAPEX1 | |
| SCHEMBL28064903 | 0.79 | MEN1 (0.42) | SMN1; SMN2POLBHPGDSYKRAB9A | |
| SCHEMBL1877385 | 0.79 | SIRT3 (0.65) | SIRT3TDP1SMN1; SMN2SMYD3TYK2 | |
| SCHEMBL7344134 | 0.78 | POLB (0.53) | SMN1; SMN2POLBHPGDSYKL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105451558-A | Pyrazolyl pyrrolinones and their use as herbicides | SYNGENTA PARTICIPATIONS AG | 2016-03-30 | — | — | CN | disclosed |