SCHEMBL28828293

SCHEMBL28828293

CCCCOC([SiH3])(OCC)[C](C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.32
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28065551 0.82 ALDH1A1 (0.36) ALDH1A1
SCHEMBL1189487 0.73 ADRB2 (0.36) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL3913186 0.69 ALDH1A1 (0.39) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL449530 0.69 ADRB2 (0.41) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL14760341 0.68 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL3886637 0.67 ADRB2 (0.39) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL940932 0.67 TSHR (0.36) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL8989147 0.66 ADRB2 (0.38) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL13092148 0.66 ADRB2 (0.38) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL10348467 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105566373-A Novel bisalkoxysilane compound and its production method SHINETSU CHEMICAL CO 2016-05-11 CN disclosed