Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 6/20 | 0.46 |
| ▸ | CCND1 | P24385 | 6/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28066227 | 0.92 | KIF11 (0.47) | KIF11BCHECDK4CCND1HTR2B | |
| SCHEMBL28066196 | 0.89 | KIF11 (0.53) | KIF11BCHEPARP14HPGDMAPK1 | |
| SCHEMBL29407801 | 0.87 | KIF11 (0.57) | KIF11BCHECDK4CCND1HTR2B | |
| SCHEMBL208888 | 0.87 | KIF11 (0.57) | KIF11BCHECDK4CCND1HTR2B | |
| SCHEMBL1326376 | 0.87 | KIF11 (0.57) | KIF11BCHECDK4CCND1HTR2B | |
| SCHEMBL30641449 | 0.87 | KIF11 (0.57) | KIF11BCHECDK4CCND1HTR2B | |
| SCHEMBL38828 | 0.87 | KIF11 (0.57) | KIF11BCHECDK4CCND1HTR2B | |
| SCHEMBL28066221 | 0.85 | BCHE (0.59) | KIF11BCHECDK4CCND1HTR2B | |
| SCHEMBL1461119 | 0.85 | KIF11 (0.52) | KIF11BCHECDK4CCND1CCNB2 | |
| SCHEMBL1326378 | 0.85 | KIF11 (0.55) | KIF11BCHECDK4CCND1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105531262-B | 2- aminocarbazole compounds and application thereof | 东曹株式会社 | 2018-05-08 | — | — | CN | disclosed |
| CN-105531262-A | 2-aminocarbazole compound and use thereof | TOSOH CORP | 2016-04-27 | — | — | CN | disclosed |