Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 4/20 | 0.45 |
| ▸ | CCND1 | P24385 | 4/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR5A | P47898 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828330 | 0.92 | KIF11 (0.49) | KIF11BCHECDK4CCND1CYP11B1 | |
| SCHEMBL187300 | 0.89 | KIF11 (0.53) | KIF11BCHECDK4CCND1CCNB2 | |
| SCHEMBL29394785 | 0.89 | KIF11 (0.53) | KIF11BCHECDK4CCND1CCNB2 | |
| SCHEMBL28066197 | 0.88 | BCHE (0.56) | KIF11BCHECDK4CCND1CCNB2 | |
| SCHEMBL28066196 | 0.87 | KIF11 (0.53) | KIF11BCHEPARP14HPGDMAPK1 | |
| SCHEMBL867558 | 0.87 | KIF11 (0.52) | KIF11BCHECDK4CCND1CCNB2 | |
| SCHEMBL30950767 | 0.87 | KIF11 (0.52) | KIF11BCHECDK4CCND1CCNB2 | |
| SCHEMBL30578643 | 0.86 | TDO2 (0.44) | KIF11BCHECDK4CCND1CCNB2 | |
| SCHEMBL30603086 | 0.86 | TDO2 (0.39) | KIF11BCHECDK4CCND1CCNB2 | |
| SCHEMBL1071406 | 0.85 | KIF11 (0.50) | KIF11BCHECDK4CCND1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105531262-B | 2- aminocarbazole compounds and application thereof | 东曹株式会社 | 2018-05-08 | — | — | CN | disclosed |
| CN-105531262-A | 2-aminocarbazole compound and use thereof | TOSOH CORP | 2016-04-27 | — | — | CN | disclosed |