SCHEMBL28828335

SCHEMBL28828335

CC(C)CC(=O)OCC(C)(C)Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.39
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MMP9 P14780 1/20 0.38
MMP13 P45452 1/20 0.38
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PRKCA P17252 2/20 0.35
CA2 P00918 1/20 0.33
GAA P10253 2/20 0.33
PRKD3 O94806 1/20 0.32
PRKCG P05129 1/20 0.32
PRKCB P05771 1/20 0.32
PRKCH P24723 1/20 0.32
PRKCI P41743 1/20 0.32
PRKCE Q02156 1/20 0.32
PRKCQ Q04759 1/20 0.32
PRKCZ Q05513 1/20 0.32
PRKCD Q05655 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3442983 0.83 MMP1 (0.41) CYP2C19MMP1MMP2MMP3MMP9
SCHEMBL8215989 0.83 MMP1 (0.41) CYP2C19MMP1MMP2MMP3MMP9
SCHEMBL8216917 0.80 MMP1 (0.42) CYP2C19MMP1MMP2MMP3MMP9
SCHEMBL12192460 0.79 MMP1 (0.38) MMP1MMP2MMP3MMP9MMP13
SCHEMBL11552293 0.79 MMP1 (0.35) CYP2C19MMP1MMP2MMP3MMP9
SCHEMBL11555153 0.79 MMP1 (0.35) CYP2C19MMP1MMP2MMP3MMP9
SCHEMBL18908741 0.78 MMP1 (0.37) CYP2C19MMP1MMP2MMP3MMP9
SCHEMBL2690771 0.77 HTT (0.50) CYP2C19MMP1MMP2MMP3MMP9
SCHEMBL3095915 0.76 MMP1 (0.40) MMP1MMP2MMP3MMP9MMP13
SCHEMBL24502636 0.76 ALDH1A1 (0.38) CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105693504-A Preparation method of gemfibrozil 康普药业股份有限公司 2016-06-22 CN disclosed