Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121322 | 1.00 | CSNK2A1 (0.39) | CSNK2A1BTKMPIMAPTHSD17B10 | |
| SCHEMBL28828441 | 0.95 | BACE1 (0.39) | MPIS1PR1HTR2CBACE1 | |
| SCHEMBL29121332 | 0.95 | BACE1 (0.39) | MPIS1PR1HTR2CBACE1 | |
| SCHEMBL28828443 | 0.92 | ERN1 (0.39) | MAPTHSD17B10 | |
| SCHEMBL29121231 | 0.92 | ERN1 (0.39) | MAPTHSD17B10 | |
| SCHEMBL29228259 | 0.90 | CSNK2A1 (0.37) | CSNK2A1BTK | |
| SCHEMBL29121275 | 0.89 | MAPT (0.36) | MAPTHSD17B10S1PR1BACE1 | |
| SCHEMBL29121340 | 0.88 | BTK (0.39) | BTKMAPTHSD17B10S1PR1HTR2C | |
| SCHEMBL28828576 | 0.88 | BTK (0.39) | BTKMAPTHSD17B10S1PR1HTR2C | |
| SCHEMBL29121357 | 0.87 | KMO (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |