Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 11/20 | 0.37 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29228413 | 0.95 | PPARA (0.40) | PPARAPPARGPPARD | |
| SCHEMBL29228388 | 0.92 | ERN1 (0.38) | PPARAPPARGPPARD | |
| SCHEMBL28828435 | 0.90 | CSNK2A1 (0.39) | CSNK2A1BTK | |
| SCHEMBL29121322 | 0.90 | CSNK2A1 (0.39) | CSNK2A1BTK | |
| SCHEMBL29228359 | 0.89 | BTK (0.38) | BTKPPARAPPARG | |
| SCHEMBL29228281 | 0.87 | PTGS2 (0.38) | — | |
| SCHEMBL29121177 | 0.86 | PPARD (0.38) | PPARAPPARD | |
| SCHEMBL29121332 | 0.85 | BACE1 (0.39) | PPARAPPARG | |
| SCHEMBL28828441 | 0.85 | BACE1 (0.39) | PPARAPPARG | |
| SCHEMBL29228228 | 0.85 | SLC6A3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746422-B | Derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | claimed |
| CN-114746422-A | Novel derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2022-07-12 | — | — | CN | claimed |
| CN-114746422-B | Derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | disclosed |
| CN-114746422-A | Novel derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2022-07-12 | — | — | CN | disclosed |