Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 8/20 | 0.43 |
| ▸ | RXRA | P19793 | 7/20 | 0.43 |
| ▸ | RXRG | P48443 | 3/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828557 | 0.90 | RXRA (0.34) | RXRBRXRADHODH | |
| SCHEMBL28828619 | 0.88 | RXRA (0.43) | RXRBRXRADHODH | |
| SCHEMBL28828366 | 0.88 | DHODH (0.39) | RXRBRXRARXRGDHODH | |
| SCHEMBL29121186 | 0.88 | DHODH (0.39) | RXRBRXRARXRGDHODH | |
| SCHEMBL28828538 | 0.85 | SSTR2 (0.35) | — | |
| SCHEMBL28828382 | 0.84 | DHODH (0.36) | DHODH | |
| SCHEMBL28828509 | 0.81 | MCL1 (0.34) | — | |
| SCHEMBL28828457 | 0.81 | KIF11 (0.44) | — | |
| SCHEMBL28828610 | 0.80 | RXRA (0.34) | RXRBRXRA | |
| SCHEMBL28828556 | 0.80 | F2R (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |