Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.34 |
| ▸ | BACE1 | P56817 | 8/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
| ▸ | F2R | P25116 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28950173 | 0.91 | KLKB1 (0.36) | PGR | |
| SCHEMBL28828530 | 0.91 | F2R (0.40) | PGRBACE1F2RCTSD | |
| SCHEMBL28828556 | 0.90 | F2R (0.35) | PGRBACE1APPF2RABCB1 | |
| SCHEMBL28828437 | 0.88 | PGR (0.34) | PGRWNT1DYRK1A | |
| SCHEMBL28828541 | 0.85 | PGR (0.36) | PGRBACE1APPCTSD | |
| SCHEMBL28828381 | 0.85 | KIF11 (0.34) | PGR | |
| SCHEMBL28828623 | 0.84 | JAK2 (0.35) | PGR | |
| SCHEMBL28950182 | 0.84 | APP (0.38) | BACE1APP | |
| SCHEMBL28828538 | 0.84 | SSTR2 (0.35) | BACE1APPF2R | |
| SCHEMBL28828603 | 0.83 | PGR (0.40) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |