Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 7/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121368 | 1.00 | PTGS2 (0.45) | PTGS2DHODHKDM1AKDM1BRXRA | |
| SCHEMBL29121270 | 0.93 | CTSA (0.38) | PTGS2DHODHKDM1AKDM1BFFAR1 | |
| SCHEMBL28828564 | 0.93 | CTSA (0.38) | PTGS2DHODHKDM1AKDM1BFFAR1 | |
| SCHEMBL29121342 | 0.92 | MCL1 (0.39) | PTGS2DHODHKDM1AKDM1BCHRM3 | |
| SCHEMBL28828555 | 0.92 | MCL1 (0.39) | PTGS2DHODHKDM1AKDM1BCHRM3 | |
| SCHEMBL29121185 | 0.91 | PTGS2 (0.43) | PTGS2DHODHKDM1AKDM1BRXRA | |
| SCHEMBL28828358 | 0.90 | DHODH (0.39) | PTGS2DHODHKDM1AKDM1BFFAR1 | |
| SCHEMBL29121352 | 0.90 | DHODH (0.39) | PTGS2DHODHKDM1AKDM1BFFAR1 | |
| SCHEMBL29121273 | 0.89 | KDM1A (0.50) | DHODHKDM1AKDM1BFFAR1MAPT | |
| SCHEMBL28828694 | 0.89 | KDM1A (0.50) | DHODHKDM1AKDM1BFFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |