Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121273 | 1.00 | KDM1A (0.50) | KDM1AKDM1BAKR1C3AKR1C2DHODH | |
| SCHEMBL29121218 | 0.90 | KDM1A (0.39) | KDM1AKDM1BAKR1C3AKR1C2DHODH | |
| SCHEMBL29121257 | 0.90 | KDM1A (0.48) | KDM1AKDM1BAKR1C3AKR1C2DHODH | |
| SCHEMBL28828494 | 0.90 | KDM1A (0.39) | KDM1AKDM1BAKR1C3AKR1C2DHODH | |
| SCHEMBL28828560 | 0.89 | AKR1C3 (0.37) | KDM1AKDM1BAKR1C3AKR1C2FFAR1 | |
| SCHEMBL28828664 | 0.89 | PTGS2 (0.45) | KDM1AKDM1BAKR1C3AKR1C2DHODH | |
| SCHEMBL28828506 | 0.89 | CYP1A1 (0.40) | KDM1AKDM1BDHODHSLC9A1NCOA1 | |
| SCHEMBL28828510 | 0.89 | PRKAB2 (0.39) | KDM1AKDM1BFFAR1 | |
| SCHEMBL28950175 | 0.89 | F2R (0.37) | KDM1AKDM1BSLC9A1LMNAALDH1A1 | |
| SCHEMBL29121219 | 0.89 | PRKAB2 (0.39) | KDM1AKDM1BFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |