Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | CPS1 | P31327 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121265 | 1.00 | AKR1C3 (0.38) | AKR1C3AKR1C2GRM2APPCYP2C19 | |
| SCHEMBL28828390 | 0.92 | FFAR1 (0.42) | APPKDM1AKDM1BFFAR1 | |
| SCHEMBL29228297 | 0.90 | GRM2 (0.41) | AKR1C3AKR1C2GRM2APPCYP2C19 | |
| SCHEMBL29121229 | 0.90 | GRM2 (0.41) | AKR1C3AKR1C2GRM2APPCYP2C19 | |
| SCHEMBL28828676 | 0.89 | CYP1A1 (0.45) | CYP2C19CTSAERN1SMN1; SMN2 | |
| SCHEMBL28828394 | 0.88 | DYRK1A (0.36) | CYP2C19SMN1; SMN2FFAR1 | |
| SCHEMBL28828624 | 0.88 | TDP2 (0.41) | GRM2APPCYP2C19KLKB1 | |
| SCHEMBL29121279 | 0.88 | FASN (0.42) | CYP2C19SMN1; SMN2 | |
| SCHEMBL28828433 | 0.87 | AKR1C3 (0.34) | AKR1C3AKR1C2GRM2APPCYP2C19 | |
| SCHEMBL28828605 | 0.87 | GRM2 (0.41) | GRM2KDM1AKDM1BSMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |