Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 8/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828984 | 0.85 | APEX1 (0.46) | AKR1B10POLBTSHRAPEX1HSD17B10 | |
| SCHEMBL28828864 | 0.84 | GRIN1 (0.41) | GRIN1GRIN2B | |
| SCHEMBL28828790 | 0.84 | TSHR (0.50) | POLBTSHRHSD17B10 | |
| SCHEMBL28828872 | 0.83 | POLB (0.44) | AKR1B10POLBTSHRAPEX1HSD17B10 | |
| SCHEMBL28828920 | 0.75 | AVPR2 (0.43) | — | |
| SCHEMBL28828912 | 0.75 | AVPR2 (0.43) | — | |
| SCHEMBL28828908 | 0.73 | TSHR (0.50) | POLBTSHRHSD17B10 | |
| SCHEMBL166328 | 0.72 | MAPT (0.48) | AKR1B10POLBTSHRAPEX1HSD17B10 | |
| SCHEMBL10469560 | 0.71 | AKR1B10 (0.42) | AKR1B10POLBTSHRAPEX1HSD17B10 | |
| SCHEMBL28828967 | 0.71 | TSHR (0.48) | POLBTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835688-B | Substituted 4-aryl imidazole-2-ketone derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-114835688-A | Substituted 4-aryl imidazole-2-ketone derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-08-02 | — | — | CN | disclosed |