Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 8/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828838 | 0.87 | GRIN1 (0.40) | GRIN1GRIN2BAVPR2AVPR1AMAPT | |
| SCHEMBL28829055 | 0.85 | GRIN1 (0.38) | GRIN1GRIN2BAVPR2AVPR1AMAPT | |
| SCHEMBL28828841 | 0.84 | AKR1B10 (0.44) | GRIN1GRIN2B | |
| SCHEMBL28828790 | 0.80 | TSHR (0.50) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28828912 | 0.79 | AVPR2 (0.43) | AVPR2AVPR1A | |
| SCHEMBL28828920 | 0.79 | AVPR2 (0.43) | AVPR2AVPR1A | |
| SCHEMBL168320 | 0.76 | APOBEC3G (0.45) | GRIN1GRIN2BAVPR2AVPR1AMAPT | |
| SCHEMBL28829027 | 0.75 | ALDH1A1 (0.42) | GRIN1GRIN2BAVPR2AVPR1AMAPT | |
| SCHEMBL28828984 | 0.70 | APEX1 (0.46) | GRIN1GRIN2BKDM4EALDH1A1HPGD | |
| SCHEMBL28828908 | 0.69 | TSHR (0.50) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835688-A | Substituted 4-aryl imidazole-2-ketone derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-08-02 | — | — | CN | disclosed |