Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL28533789 | 0.98 | FFAR4 (0.60) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Terephthalic Acid SCHEMBL28992734 | 0.95 | FFAR4 (0.50) | FFAR4FFAR1AKR1B1TSHRALDH1A1 | |
| Terephthalic Acid SCHEMBL8840756 | 0.92 | RARB (0.54) | TSHRALDH1A1MEN1KMT2ATP53 | |
| Terephthalic Acid SCHEMBL11562692 | 0.92 | RARB (0.54) | TSHRALDH1A1MEN1KMT2ATP53 | |
| Terephthalic Acid SCHEMBL28561064 | 0.90 | FFAR4 (0.47) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Terephthalic Acid SCHEMBL2422481 | 0.90 | FFAR4 (0.47) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Terephthalic Acid SCHEMBL30402864 | 0.90 | TP53 (0.57) | GPR84TSHRALDH1A1MEN1KMT2A | |
| Terephthalic Acid SCHEMBL29199869 | 0.90 | TP53 (0.57) | GPR84TSHRALDH1A1MEN1KMT2A | |
| Terephthalic Acid SCHEMBL28005583 | 0.90 | TP53 (0.57) | GPR84TSHRALDH1A1MEN1KMT2A | |
| Sebacic Acid SCHEMBL28189363 | 0.89 | FFAR4 (0.50) | FFAR4FFAR1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119895007-A | Moisture-curable polyurethane hot melt adhesive compositions | 汉高股份有限及两合公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-118613563-A | Reactive hot melt adhesive composition and use thereof | 汉高股份有限及两合公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-118355088-A | Moisture-curable polyurethane hot melt adhesive compositions | 汉高股份有限及两合公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-114008165-B | Moisture curable polyurethane hot melt adhesive compositions with low levels of diisocyanate monomer | H.B.富乐公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116635501-A | Oil resistant adhesive composition | 汉高股份有限及两合公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-114846107-A | Polyurethane hot melt adhesive composition and method for preparing same | 汉高股份有限及两合公司 | 2022-08-02 | — | — | CN | disclosed |