Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sebacic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL2422481 | 0.98 | FFAR4 (0.47) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| Terephthalic Acid SCHEMBL28561064 | 0.98 | FFAR4 (0.47) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| Terephthalic Acid SCHEMBL28186890 | 0.92 | GPR84 (0.44) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| Terephthalic Acid SCHEMBL28768369 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TSHRSLC22A6SLC22A8KMT2A | |
| Terephthalic Acid SCHEMBL2420235 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TSHRSLC22A6SLC22A8KMT2A | |
| Terephthalic Acid SCHEMBL28186870 | 0.91 | FFAR4 (0.41) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| Terephthalic Acid SCHEMBL28827201 | 0.91 | FFAR4 (0.41) | FFAR4FFAR1ALDH1A1TDP1 | |
| Dodecanoate SCHEMBL28533789 | 0.90 | FFAR4 (0.60) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| Terephthalic Acid SCHEMBL28828873 | 0.89 | FFAR4 (0.57) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| Terephthalic Acid SCHEMBL28003612 | 0.88 | SMN1; SMN2 (0.42) | FFAR4FFAR1ALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384364-A | Biodegradable polyester elastomer toughening particles, polyglycolic acid composition and preparation method | 中船鹏力(南京)塑造科技有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117384364-A | Biodegradable polyester elastomer toughening particles, polyglycolic acid composition and preparation method | 中船鹏力(南京)塑造科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-115197405-A | Degradable PBSeT copolyester material with water vapor barrier property based on furan ring and preparation method thereof | 中北大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-105440268-B | A kind of aliphatic aromatic PLA segmented copolymer | 中国科学院长春应用化学研究所 | 2018-02-13 | — | — | CN | disclosed |