Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 3/20 | 0.64 |
| ▸ | CTSL | P07711 | 2/20 | 0.59 |
| ▸ | CTSS | P25774 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.59 |
| ▸ | TACR3 | P29371 | 1/20 | 0.59 |
| ▸ | NMBR | P28336 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182380 | 1.00 | SPR (0.64) | SPRCTSLCTSSCTSKTRPV1 | |
| SCHEMBL29804661 | 1.00 | SPR (0.64) | SPRCTSLCTSSCTSKTRPV1 | |
| SCHEMBL29616348 | 1.00 | SPR (0.64) | SPRCTSLCTSSCTSKTRPV1 | |
| SCHEMBL7448187 | 0.89 | CTSL (0.56) | SPRCTSLCTSSCTSKNMBR | |
| SCHEMBL4112957 | 0.86 | ACE (0.62) | CTSLCTSSCTSKMAPTKDM4E | |
| SCHEMBL4108869 | 0.86 | ACE (0.62) | CTSLCTSSCTSKMAPTKDM4E | |
| SCHEMBL21292790 | 0.86 | ACE (0.62) | CTSLCTSSCTSKMAPTKDM4E | |
| SCHEMBL29804225 | 0.86 | ACE (0.62) | CTSLCTSSCTSKMAPTKDM4E | |
| SCHEMBL31077788 | 0.86 | TRPV1 (0.70) | SPRTRPV1MAPTKDM4EALDH1A1 | |
| SCHEMBL798165 | 0.86 | TRPV1 (0.70) | SPRTRPV1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114828900-A | High efficiency myeloperoxidase activatable imaging agents | 总医院公司 | 2022-07-29 | — | — | CN | disclosed |