Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352821 | 0.79 | CHRNB4 (0.43) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL6940509 | 0.74 | CHRNB4 (0.50) | CHRNB4CHRNA3IDO1HTR2CPDPK1 | |
| SCHEMBL3425103 | 0.74 | CHRNB4 (0.50) | CHRNB4CHRNA3IDO1HTR2CPDPK1 | |
| SCHEMBL779515 | 0.71 | SLC18A3 (0.43) | — | |
| SCHEMBL23797352 | 0.69 | CHRNB4 (0.59) | CHRNB4CHRNA3IDO1HTR2CPDPK1 | |
| SCHEMBL13815519 | 0.69 | HTR2A (0.35) | CHRNB4CHRNA3IDO1HTR2CPDPK1 | |
| SCHEMBL1201800 | 0.69 | HTR2A (0.35) | CHRNB4CHRNA3IDO1HTR2CPDPK1 | |
| SCHEMBL221689 | 0.69 | CHRNB4 (0.59) | CHRNB4CHRNA3IDO1HTR2CPDPK1 | |
| SCHEMBL30166929 | 0.69 | CHRNB4 (0.59) | CHRNB4CHRNA3IDO1HTR2CPDPK1 | |
| SCHEMBL2913620 | 0.67 | CHRNB4 (0.44) | CHRNB4CHRNA3IDO1HTR2CPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115176005-A | Compositions and methods for treating hemoglobinopathies | 诺华股份有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-114828959-A | 3- (5-methoxy-1-oxoisoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof | 诺华股份有限公司 | 2022-07-29 | — | — | CN | disclosed |