Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002087 | 0.79 | TSHR (0.43) | ALDH1A1ALOX5MAPTHPGDMAPK1 | |
| SCHEMBL7045980 | 0.78 | ALDH1A1 (0.55) | ALDH1A1ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL5425024 | 0.73 | TSHR (0.40) | ALDH1A1MAPTMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL194803 | 0.72 | TSHR (0.57) | ALDH1A1ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL4869141 | 0.71 | TSHR (0.39) | ALDH1A1MAPTHPGDMAPK1L3MBTL1 | |
| SCHEMBL11687302 | 0.70 | TSHR (0.55) | ALDH1A1ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL9052472 | 0.69 | TSHR (0.48) | ALDH1A1PTGS1PTGS2MAPTMAOB | |
| SCHEMBL383496 | 0.69 | TSHR (0.48) | ALDH1A1PTGS1PTGS2MAPTMAOB | |
| Carbon Monoxide SCHEMBL11680342 | 0.69 | TSHR (0.48) | ALDH1A1PTGS1PTGS2HCAR2MAPK1 | |
| SCHEMBL11189042 | 0.69 | CA12 (0.54) | ALDH1A1MAPTHPGDHCAR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105637013-A | Method for producing polyether carbonate polyols | COVESTRO DEUTSCHLAND AG | 2016-06-01 | — | — | CN | disclosed |