SCHEMBL30002087

SCHEMBL30002087

CN(C)OP(OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
ALDH1A1 P00352 4/20 0.40
IDO1 P14902 1/20 0.40
AGXT P21549 1/20 0.39
AOC3 Q16853 2/20 0.38
TAAR1 Q96RJ0 1/20 0.38
MAPT P10636 2/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HPGD P15428 1/20 0.37
ALOX5 P09917 1/20 0.36
MGLL Q99685 1/20 0.35
OPRM1 P35372 1/20 0.35
OPRL1 P41146 1/20 0.35
AR P10275 1/20 0.35
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5425024 0.81 TSHR (0.40) TSHRALDH1A1IDO1AGXTAOC3
SCHEMBL194803 0.80 TSHR (0.57) TSHRALDH1A1IDO1AGXTMAPT
SCHEMBL4869141 0.79 TSHR (0.39) TSHRALDH1A1IDO1AGXTTAAR1
SCHEMBL28829301 0.79 ALDH1A1 (0.47) ALDH1A1MAPTMAPK1TDP1L3MBTL1
SCHEMBL11687302 0.78 TSHR (0.55) TSHRALDH1A1IDO1AGXTMAPT
SCHEMBL383496 0.77 TSHR (0.48) TSHRALDH1A1IDO1AGXTMAPT
SCHEMBL9052472 0.77 TSHR (0.48) TSHRALDH1A1IDO1AGXTMAPT
Bromide SCHEMBL11675628 0.76 TSHR (0.52) TSHRALDH1A1IDO1AGXTMAPT
SCHEMBL7934188 0.76 TSHR (0.52) TSHRALDH1A1IDO1AGXTMAPT
SCHEMBL1552017 0.76 TSHR (0.39) TSHRALDH1A1IDO1AGXTTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115190893-A Method for producing polyether carbonate polyols 科思创德国股份有限公司 2022-10-14 CN disclosed