SCHEMBL28829633

SCHEMBL28829633

c1ccc2c(c1)ccc1cc3c4c(cccc4c12)CC3

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.44
HPGD P15428 8/20 0.44
KDM4E B2RXH2 6/20 0.44
MAPT P10636 4/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
GAA P10253 2/20 0.44
LMNA P02545 2/20 0.44
POLB P06746 2/20 0.41
ATM Q13315 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP1A2 P05177 3/20 0.40
FYN P06241 2/20 0.40
ACHE P22303 2/20 0.40
AHR P35869 2/20 0.40
ERBB2 P04626 1/20 0.40
MAOA P21397 1/20 0.40
HSD17B10 Q99714 6/20 0.39
TSHR P16473 4/20 0.39
CYP2A6 P11509 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12753 0.82 ALDH1A1 (0.48) ALDH1A1HPGDKDM4EMAPTMEN1
SCHEMBL29765599 0.82 ALDH1A1 (0.48) ALDH1A1HPGDKDM4EMAPTMEN1
Phenanthrene SCHEMBL27970728 0.78 ALDH1A1 (0.55) ALDH1A1HPGDKDM4EMAPTMEN1
SCHEMBL4856741 0.77 TSHR (0.57) ALDH1A1HPGDKDM4EMAPTKMT2A
Fluoranthene SCHEMBL29286799 0.74 ALDH1A1 (0.58) ALDH1A1HPGDKDM4EMAPTMEN1
Cholanthrene SCHEMBL9048 0.74 ALDH1A1 (0.65) ALDH1A1HPGDKDM4EMAPTMEN1
SCHEMBL11681631 0.74 ALDH1A1 (0.43) ALDH1A1HPGDKDM4EMAPTMEN1
Acenaphthene SCHEMBL28444594 0.73 ALDH1A1 (0.50) ALDH1A1HPGDKDM4EMAPTMEN1
SCHEMBL4852490 0.72 ALDH1A1 (0.56) ALDH1A1HPGDMAPTATMCYP1A2
SCHEMBL3633408 0.72 HPRT1 (0.48) ALDH1A1HPGDKDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114846114-B Polycyclic compound and organic light-emitting device using the same SFC株式会社 2024-07-23 CN disclosed
CN-114761415-B Polycyclic compound and organic electroluminescent device using the same SFC株式会社 2024-07-19 CN disclosed
CN-114846114-A Polycyclic compound and organic light-emitting device using the same SFC株式会社 2022-08-02 CN disclosed