Cholanthrene

Cholanthrene

SCHEMBL9048

c1cc2c3c(c4ccc5ccccc5c4cc3c1)CC2

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.65
CYP1A2 P05177 5/20 0.65
FYN P06241 2/20 0.65
ACHE P22303 2/20 0.65
AHR P35869 2/20 0.65
MAPT P10636 2/20 0.65
LCK P06239 1/20 0.65
ADORA3 P0DMS8 1/20 0.65
SLC6A2 P23975 1/20 0.65
ERBB2 P04626 1/20 0.44
MAOA P21397 1/20 0.44
HSD17B10 Q99714 5/20 0.44
HIF1A Q16665 1/20 0.44
CYP1B1 Q16678 1/20 0.44
HPRT1 P00492 4/20 0.42
CYP2A6 P11509 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8955 0.82 CYP1A2 (0.46) ALDH1A1CYP1A2FYNACHEAHR
SCHEMBL28783299 0.81 CYP1A2 (0.62) ALDH1A1CYP1A2FYNACHEAHR
SCHEMBL9347612 0.81 CYP1A2 (0.55) ALDH1A1CYP1A2FYNACHEAHR
Acenaphthene SCHEMBL28870353 0.79 CYP1A2 (0.47) ALDH1A1CYP1A2FYNACHEAHR
3-Methylcholanthrene SCHEMBL29397062 0.79 ALDH1A1 (1.00) ALDH1A1CYP1A2FYNACHEAHR
SCHEMBL4847809 0.79 ALDH1A1 (0.51) ALDH1A1CYP1A2FYNACHEAHR
3-Methylcholanthrene SCHEMBL29444145 0.79 ALDH1A1 (1.00) ALDH1A1CYP1A2FYNACHEAHR
3-Methylcholanthrene SCHEMBL156129 0.79 ALDH1A1 (1.00) ALDH1A1CYP1A2FYNACHEAHR
SCHEMBL3345885 0.78 ALDH1A1 (0.67) ALDH1A1CYP1A2FYNACHEAHR
Phenanthrene SCHEMBL27970728 0.78 ALDH1A1 (0.55) ALDH1A1CYP1A2FYNACHEAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114644543-B Method and device for separating and purifying 1-dodecene from Fischer-Tropsch synthesis stable heavy oil 国家能源集团宁夏煤业有限责任公司 2024-01-16 CN claimed
US-8866383-B2 Flat display device with multilayer sealing layer having oxygen-free buffer layer and method of manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-21 US claimed
US-20140015401-A1 FLAT DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US claimed
CN-1296331-C Method for deuteration of aromatic ring WAKO PURE CHEM IND LTD (JP) 2007-01-24 CN claimed
CN-1675145-A Method of deuterating aromatic ring WAKO PURE CHEM IND LTD (JP) 2005-09-28 CN claimed
US-4495089-A PARTIAL HJYDROGENATION OF TRI-, TETRA-AND PENTACYLIC AROMATIC HYDRDROCARBONSINPRESENCE OF PHEONO OR ALKYLPHENOLS MITSUBISHI OIL COMPANY, LIMITED (JP) 1985-01-22 US claimed
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor BRILLIANT LIGHT POWER, INC. (US) 2026-02-03 US disclosed
US-20250340519-A1 RADIOLABELLED COMPOUND OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2025-11-06 US disclosed
EP-4624459-A2 RADIOLABELLED COMPOUND Oxford University Innovation Limited (GB) 2025-10-01 EP disclosed
WO-2025132734-A1 ANIONIC CONDUCTOR OXECO U.K. LIMITED (GB) 2025-06-26 WO disclosed
CN-114521299-B Organic electroluminescent element and method for manufacturing the same 日铁化学材料株式会社 2025-05-13 CN disclosed
CN-113710770-B Organic electroluminescent element and method for manufacturing the same 日铁化学材料株式会社 2024-12-31 CN disclosed
US-20240383827-A1 DIFLUOROCARBENE RADIOSYNTHESIS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2024-11-21 US disclosed
CN-1265149-A Use of MHC-11-class ligands as vaccine adjuvants and LAG-3 for cancer treatment ROUSSY INST GUSTAVE (FR) 2000-08-30 CN disclosed
EP-0979303-A1 METHOD AND APPARATUS FOR PREPARATION OF CHIRAL BETA AMINO ACIDS G.D. SEARLE & CO. (US) 2000-02-16 EP disclosed
EP-0771786-B1 Preparation of aryl and vinyl nitriles LILLY CO ELI (US) 2000-02-16 EP disclosed
WO-1998050575-A1 METHOD AND APPARATUS FOR PREPARATION OF CHIRAL BETA AMINO ACIDS G.D. SEARLE & CO. (US) 1998-11-12 WO disclosed
WO-1997016414-A1 PREPARATION OF ARYL AND VINYL NITRILES ELI LILLY AND COMPANY (US) 1997-05-09 WO disclosed
EP-0771786-A1 Preparation of aryl and vinyl nitriles ELI LILLY AND COMPANY (US) 1997-05-07 EP disclosed
US-4495089-A PARTIAL HJYDROGENATION OF TRI-, TETRA-AND PENTACYLIC AROMATIC HYDRDROCARBONSINPRESENCE OF PHEONO OR ALKYLPHENOLS MITSUBISHI OIL COMPANY, LIMITED (JP) 1985-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340519-A1 RADIOLABELLED COMPOUND PARP3, PARP2, PARP1 ALDH1A1 632/4885CYP1A2 1388/4885FYN 2339/4885
US-20240383827-A1 DIFLUOROCARBENE RADIOSYNTHESIS RFC2, FDFT1, AFF1 ALDH1A1 303/4885CYP1A2 355/4885FYN 519/4885
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor SCO2, SOD1, HAO2 ALDH1A1 3874/4885CYP1A2 1592/4885FYN 369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.