Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505735 | 0.78 | MAPT (0.58) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL29078839 | 0.74 | ALDH1A1 (0.58) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL8069296 | 0.74 | MAPT (0.46) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL8069292 | 0.74 | MAPT (0.46) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL9229616 | 0.74 | ALDH1A1 (0.51) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL3262089 | 0.73 | MAPT (1.00) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL29516939 | 0.73 | MAPT (1.00) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL29084195 | 0.73 | CHRM2 (0.42) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL28181110 | 0.72 | HSD17B10 (0.67) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL17548633 | 0.72 | MEN1 (0.56) | NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105601555-A | Method for preparing nitroindole derivatives | UNIV SOOCHOW | 2016-05-25 | — | — | CN | disclosed |