Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829653 | 0.78 | MAPT (0.57) | MAPTALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL3160763 | 0.73 | MAPT (0.68) | MAPTALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL30099697 | 0.73 | MAPT (0.68) | MAPTALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL29516939 | 0.73 | MAPT (1.00) | MAPTALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL3262089 | 0.73 | MAPT (1.00) | MAPTALDH1A1NPSR1NPC1LMNA | |
| Nitric Acid SCHEMBL31591113 | 0.73 | GPR3 (0.67) | MAPTALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL483003 | 0.70 | GPR3 (0.61) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL31132408 | 0.70 | GPR3 (0.61) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL150552 | 0.69 | MAPT (1.00) | MAPTALDH1A1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL6285886 | 0.69 | ALKBH5 (0.54) | MAPTALDH1A1NPSR1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5001233-A | — | — | None | — | — | JP | disclosed |
| US-20240174647-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. | 2024-05-30 | — | — | US | disclosed |
| WO-2024073073-A2 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| JP-H051233-A | INDOLE COMPOUND | SEIKO EPSON CORP | 1993-01-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174647-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | LRRK2, MAP3K20, MAP3K5 | MAPT 623/4885ALDH1A1 4623/4885NPSR1 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.