Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31632748 | 0.94 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632704 | 0.94 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632691 | 0.94 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632701 | 0.94 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL782902 | 0.94 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632753 | 0.94 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632726 | 0.94 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL29988843 | 0.94 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632717 | 0.93 | LMNA (0.50) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632702 | 0.88 | CA2 (0.51) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105722858-A | IL-18 binding proteins (IL-18BP) in inflammatory diseases | AB2生物股份有限公司 | 2016-06-29 | — | — | CN | disclosed |