Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17100531 | 0.98 | TSHR (0.41) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL434543 | 0.98 | TSHR (0.41) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL30490810 | 0.96 | TSHR (0.43) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL8220006 | 0.82 | ALDH1A1 (0.40) | TSHRALDH3A1SMN1; SMN2HPGD | |
| SCHEMBL28696743 | 0.82 | MEN1 (0.36) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL28681176 | 0.81 | — | — | |
| SCHEMBL7622333 | 0.80 | ALDH1A1 (0.42) | TSHRALDH3A1SMN1; SMN2HPGD | |
| SCHEMBL11304710 | 0.77 | ALDH1A1 (0.32) | TSHRALDH3A1SMN1; SMN2HPGD | |
| SCHEMBL6577560 | 0.76 | — | — | |
| SCHEMBL11108551 | 0.75 | ALDH3A1 (0.42) | TSHRALDH3A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103930401-B | Pesticidal compounds | 先正达参股股份有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-103764634-B | N-epoxide pyrazolo-three azatropylidenes-derovatives | 先正达参股股份有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-103402979-B | Chemical compound | 先正达参股股份有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105873901-A | Insecticidal compounds | 先正达参股股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-105829324-A | PESTICIDALLY ACTIVE SUBSTITUTED 5, 5-BICYCLIC HETEROCYCLES WITH SULPHUR CONTAINING SUBSTITUENTS | 先正达参股股份有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-105722839-A | Pesticidally active bicyclic heterocycles with sulphur-containing substituents | 先正达参股股份有限公司 | 2016-06-29 | — | — | CN | disclosed |