Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 8/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826714 | 1.00 | TTR (0.54) | TTRAKR1B1STSKDM4EPOLB | |
| SCHEMBL27459905 | 0.83 | ATM (0.48) | TTRMAPTL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL71110 | 0.82 | TTR (0.68) | TTRAKR1B1STSKDM4EPOLB | |
| SCHEMBL27635848 | 0.77 | TTR (0.62) | TTRAKR1B1KDM4EMAPTMEN1 | |
| SCHEMBL68189 | 0.77 | TTR (0.83) | TTRAKR1B1STSKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL11749391 | 0.76 | TTR (0.81) | TTRAKR1B1STSKDM4EMAPT | |
| SCHEMBL11768568 | 0.76 | TTR (0.65) | TTRAKR1B1STSKDM4EMAPT | |
| SCHEMBL1259182 | 0.76 | TTR (0.56) | TTRAKR1B1STSKDM4EPOLB | |
| SCHEMBL9640769 | 0.75 | PIM1 (0.60) | TTRAKR1B1STSKDM4EPOLB | |
| SCHEMBL11439145 | 0.75 | TTR (0.59) | TTRAKR1B1STSKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981263-A | Novel quercetin redox derivatives and use thereof as BET inhibitors | 贝诺生物有限公司 | 2022-08-30 | — | — | CN | disclosed |