Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28843621 | 1.00 | MEN1 (0.47) | MEN1KMT2ANPC1KDM4EHPGD | |
| SCHEMBL20942903 | 0.79 | SMN1; SMN2 (0.41) | NPC1HPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20942904 | 0.79 | SMN1; SMN2 (0.41) | NPC1HPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL3421548 | 0.78 | KMT2A (0.54) | MEN1KMT2ANPC1KDM4EHPGD | |
| SCHEMBL4366146 | 0.78 | KMT2A (0.54) | MEN1KMT2ANPC1KDM4EHPGD | |
| SCHEMBL10433550 | 0.78 | KMT2A (0.54) | MEN1KMT2ANPC1KDM4EHPGD | |
| SCHEMBL15705122 | 0.78 | CES2 (0.48) | MEN1KMT2ANPC1HPGDALDH1A1 | |
| SCHEMBL21148116 | 0.78 | KMT2A (0.45) | MEN1KMT2ANPC1KDM4EHPGD | |
| SCHEMBL11744885 | 0.78 | CES2 (0.48) | MEN1KMT2AHPGDALDH1A1TSHR | |
| SCHEMBL10433489 | 0.75 | TSHR (0.48) | MEN1KMT2ANPC1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105611923-B | Sodium channel modulators for the treatment of pain and diabetes | 卓莫赛尔公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-105611923-A | Sodium channel modulators for the treatment of pain and diabetes | CHROMOCELL CORP | 2016-05-25 | — | — | CN | disclosed |