SCHEMBL4366146

SCHEMBL4366146

C/C=C(\C)c1ccccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.54
NPC1 O15118 2/20 0.54
MEN1 O00255 2/20 0.54
KDM4E B2RXH2 6/20 0.46
ALDH1A1 P00352 5/20 0.46
HPGD P15428 5/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
CA12 O43570 2/20 0.46
CA2 P00918 2/20 0.46
CA4 P22748 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA1 P00915 1/20 0.46
HMGB1 P09429 1/20 0.46
CA6 P23280 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
TSHR P16473 3/20 0.45
LMNA P02545 2/20 0.45
MAPT P10636 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10433550 1.00 KMT2A (0.54) KMT2ANPC1MEN1KDM4EALDH1A1
SCHEMBL3421548 1.00 KMT2A (0.54) KMT2ANPC1MEN1KDM4EALDH1A1
SCHEMBL21148116 0.81 KMT2A (0.45) KMT2ANPC1MEN1KDM4EALDH1A1
SCHEMBL16863924 0.78 KDM4E (0.54) KMT2ANPC1MEN1KDM4EALDH1A1
SCHEMBL10973737 0.78 MAPT (0.47) KMT2ANPC1MEN1KDM4EALDH1A1
SCHEMBL10433489 0.78 TSHR (0.48) KMT2ANPC1MEN1KDM4EALDH1A1
SCHEMBL7026918 0.78 RAB9A (0.51) KMT2ANPC1MEN1KDM4EALDH1A1
SCHEMBL11769972 0.78 KMT2A (0.47) KMT2ANPC1MEN1KDM4EALDH1A1
SCHEMBL6706818 0.78 KMT2A (0.47) KMT2ANPC1MEN1KDM4EALDH1A1
SCHEMBL10580310 0.78 KMT2A (0.47) KMT2ANPC1MEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021102332-A1 TGFBETAR2 INHIBITOR-LRRC15 ANTIBODY CONJUGATES AND USES THEREOF SILVERBACK THERAPEUTICS, INC. (US) 2021-05-27 WO disclosed
US-7560162-B2 Electrodeposition coating composition, coating method and coated article KANSAI PAINT CO., LTD. (JP) 2009-07-14 US disclosed
US-20060211831-A1 Electrodeposition coating composition, coating method and coated article KANSAI PAINT CO. LTD. (JP) 2006-09-21 US disclosed
EP-0448341-B1 Coating composition for precoated metal material NIPPON PAINT CO LTD (JP) 1995-06-07 EP disclosed
US-5274173-A Process for the production of poly(4-acetoxystyrene) HOECHST CELANESE CORPORATION (US) 1993-12-28 US disclosed
US-5274174-A Process for the production of poly(4-hydroxystyrene) HOECHST CELANESE CORPORATION (US) 1993-12-28 US disclosed
US-5274175-A Process for the preparation of 4-acetoxyphenylmethyl carbinol HOECHST CELANESE CORPORATION (US) 1993-12-28 US disclosed
US-5245074-A Process for the production of 4-acetoxystyrene, its polymers and hydrolysis products CLARIANT AG (CH) 1993-09-14 US disclosed
EP-0531575-A1 Corrosion-resistant precoated steel sheet suitable for electrodeposition finish coating SUMITOMO METAL INDUSTRIES, LTD. (JP) 1993-03-17 EP disclosed
US-5151546-A Process for the production of 4-acetoxystyrene, its polymers and hydrolysis products HOECHST CELANESE CORPORATION (US) 1992-09-29 US disclosed
EP-0355984-A2 Poly(epoxide) coatings containing a mannich base of a hydroxystyrene containing polymer HOECHST CELANESE CORPORATION (US) 1990-02-28 EP disclosed
EP-0352950-A2 Protective coatings of a cured hydroxystyrene mannich base and blocked polyisocyanates HOECHST CELANESE CORPORATION (US) 1990-01-31 EP disclosed
US-4877502-A Poly(epoxide) coatings containing a mannich base of a hydroxystyrene containing polymer HOECHST CELANESE CORPORATION (US) 1989-10-31 US disclosed
US-4872960-A Protective coatings of a cured hydroxystyrene mannich base and blocked polyisocyantes HOECHST CELANESE CORPORATION (US) 1989-10-10 US disclosed
EP-0178020-B1 PROCESS FOR THE TREATMENT OF ALUMINIUM SURFACES PARKER CHEMICAL COMPANY (a Delaware company) (US) 1988-10-19 EP disclosed
EP-0178020-A1 Process for the treatment of aluminium surfaces PARKER CHEMICAL COMPANY (a Delaware company) (US) 1986-04-16 EP disclosed
US-4539051-A Process for producing phosphate coatings PARKER CHEMICAL COMPANY (US) 1985-09-03 US disclosed
US-4517028-A CORROSION RESISTANT COATINGS PARKER CHEMICAL COMPANY (US) 1985-05-14 US disclosed
US-4457790-A CORROSION RESISTANCE PARKER CHEMICAL COMPANY (US) 1984-07-03 US disclosed
US-4035559-A CROSSLINKING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-07-12 US disclosed